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miR-155通过sirtuin 1/核因子-κB介导的肠道热致死诱导肠道粘膜屏障的败血症相关损伤

Zhihua Li1, Yi Wang1,2, Weiwei Huang1

  • 1The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.

Acta biochimica et biophysica Sinica
|September 12, 2024
PubMed
概括

微RNA-155 (miR-155) 通过促进烧死,加剧了败血症引起的肠损伤. 抑制miR-155可以恢复Sirtuin 1 (SIRT1) 功能,减少炎症并保护肠道屏障.

关键词:
在 NF-κBB 中.一个SIRT1系统.肠道屏障功能障碍 肠道屏障功能障碍在 miR-155 系统中,它是 miR-155 的.热致灭 (pyroptosis) 是一种致的过程.这是一种血症.

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