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在患有微心房的患者中,尿性酸度和心声学发现
Hüseyin Aykaç1, Cihan Aydın1, Aykut Demirkıran1
1Tekirdağ Namık Kemal University.
Kardiologiia
|September 12, 2024
概括
升高的N-终端亲B型尿素 (Pro-BNP) 和心房电机延迟预测微心房动 (AF). 这些标记物,以及心电图的发现,可以帮助识别患有这种沉默的AF前体风险的患者.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 生物标志物研究 生物标志物研究
背景情况:
- 心房动 (AF) 是一种常见的心律失常.
- 微型AF的特点是短暂的AF类活动,可能会在可检测的AF之前出现.
- 了解微型AF的预测因素对于早期检测和干预至关重要.
研究的目的:
- 调查微型AF患者中尿素水平与心声学发现之间的关联.
- 为了确定微型AF的潜在预测因素.
主要方法:
- 24小时霍尔特监测用于记录心患者的心电图.
- 微型AF被定义为没有P波的不规则心房动脉短暂发作 (<30秒).
- 在实验室,心电图和心声学参数方面,微型AF患者 (n=45) 与对照组 (n=45) 相比较.
主要成果:
- 在微型AF组中,N-终端亲B型尿素 (Pro-BNP) 和素T水平显著更高.
- 增加的Pro-BNP水平与更高的微型AF风险相关.
- 在微型AF组中,心房电机延迟 (环间平面AEMD和环内AEMD LEFT) 和P波持续时间/散射在心电图上显著延长.
结论:
- 微型AF可以通过评估心电图参数,心声学发现和血清 natriuretic度来预测.
- 亲BNP和心房电机延迟显示为微型AF的诊断标记物具有前途.
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