新的纳米化V(III),Fe(III) 和Ni(II) 复合物,包括希夫基和2-氨基-4-甲基胺:合成,特性和生物活性
Maged S Al-Fakeh1,2, Maha A Alsikhan1, Jawza S H Alnawmasi1
1Department of Chemistry, College of Science, Qassim University, Buraydah 51452, Saudi Arabia.
International journal of biomaterials
|September 12, 2024
概括
合成和表征了,铁和的新混合联结体复合物. 这些纳米金属复合物表现出有前途的抗菌活性,和化合物对经过测试的细菌和真菌菌株具有更高的疗效.
科学领域:
- 协调化学 协调化学
- 材料科学 材料科学 材料科学
- 抗菌剂 抗菌剂 抗菌剂
背景情况:
- 混合合金金属复合物为各种应用提供可调节的性能.
- 希夫基和胺基衍生物以其多样化的生物活性而闻名.
- 研究新型金属复合物的合成和表征对于开发新材料和治疗剂至关重要.
研究的目的:
- 合成和表征 (III),铁 (III) 和 (II) 的新型混合联结体复合物.
- 评估合成复合物的结构性,热性和微观结构性.
- 评估这些金属复合物的抗菌潜力,以对抗特定的细菌和真菌菌株.
主要方法:
- 使用希夫基 (L1) 和2-amino-4-methyl pyrimidine (L2) 合成混合联结体复合物.
- 描述技术:元素分析,分子导电性,FT-IR,UV-Vis光谱学,磁性易感性,TGA,XRD和SEM.
- 使用光盘扩散方法对细菌细菌,大肠杆菌, Pseudomonas aeruginosa 和 Aspergillus fumigatus 的抗菌活性评估.
主要成果:
- 成功合成了具有八面体几何结构的混合联结体复合体,通过磁性敏感度值 (V: 2.88 BM,Fe: 5.96 BM,Ni: 2.92 BM) 得到证实.
- 纳米复合体 (29-50nm) 具有XRD和SEM的特征,表明其热稳定性.
- 这些复合物表现出抗微生物活性, (III) 和 (II) 复合物显示出比铁 (III) 对测试病原体更大的疗效.
结论:
- 合成的混合联结体金属复合体具有八面体几何和纳米结构.
- 这些复合物表现出显著的抗微生物特性,突出了它们作为治疗剂的潜力.
- (III) 和 (II) 复合物特别有效,这表明它们对药物开发具有前景.
更多相关视频
10:51The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
12.1K
15:03Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection
Published on: June 16, 2020
9.2K
相关概念视频
02:42Valence Bond Theory
8.5K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
8.5K
03:02Colors and Magnetism
11.6K
Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
11.6K