在COVID-19后儿童中呼吸道病原体感染的流行病学趋势:一个横截面研究
Tiewei Li1, Xiaojuan Li1, Xinrui Liu1
1Department of Clinical Laboratory, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou Key Laboratory of Children's Infection and Immunity, Zhengzhou, China.
Heliyon
|September 12, 2024
概括
在COVID-19后,呼吸道病原体感染,如流感A病毒和Mycoplasma肺炎在儿童中激增. 疫情比平时更早爆发,突显了持续监测和临床关注的必要性.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- COVID-19大流行严重影响全球健康,可能改变其他传染病的流行病学.
- 了解儿科呼吸道感染的流行后趋势对于公共卫生战略至关重要.
研究的目的:
- 调查COVID-19大流行后儿童常见呼吸道病原体的流行病学趋势.
- 为了识别由A型流感病毒,B型流感病毒,呼吸道同胞病毒,腺病毒和Mycoplasma肺炎引起的感染时间和流行率的变化.
主要方法:
- 对575373名出现呼吸系统症状的儿童电子病历的回顾性分析.
- 收集流感A病毒 (IAV),流感B病毒 (IBV),呼吸道同胞性病毒 (RSV),腺病毒 (ADV) 和菌性肺炎 (MP) 测试的人口统计数据和实验室结果.
- 使用SPSS和GraphPad Prism软件进行统计分析.
主要成果:
- 对IAV (28.5%),MP (15.5%),ADV (11.9%),RSV (7.1%) 和IBV (1.1%) 观察到显著的阳性率.
- 对IAV,RSV,ADV和MP的感染高峰期比前几年更早,在特定的月份出现了显著的激增.
- 3岁以上的儿童主要受到IAV,IBV,ADV和MP的影响,而RSV主要影响6岁以下的儿童.
结论:
- 呼吸道病原体感染在COVID-19后的儿童中表现出明显的流行趋势.
- 这些发现强调了及时监测儿科呼吸道病原体流行病学的重要性,以告知公共卫生和临床实践.
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