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与健康对照人群相比,在预防的双极性疾病患者中,超声波确定甲状腺体体积,与健康对照人群相比
Anjali Bhasin1, Devasenathipathy Kandasamy2, Yashdeep Gupta3
1Dr. Bhasin, Formerly, Junior Resident, Department of Psychiatry, All India Institute of Medical Sciences (AIIMS), New Delhi, India, Present Affiliation: Senior Resident, Institute of Liver and Biliary Sciences, New Delhi, India.
Psychopharmacology bulletin
|September 12, 2024
概括
对双相情感障碍 (BD) 的治疗显著增加了甲状腺体体积. 这项研究发现,在接受治疗的BD患者中,甲状腺腺扩大,与甲状腺功能或反应无关.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 医疗成像医学成像
背景情况:
- 是双相情感障碍 (BD) 的首要治疗方法.
- 长期接触可以改变甲状腺的大小,结构和功能.
- 甲状腺超声波对于检测结构异常是有价值的,但在使用者中报告不足.
研究的目的:
- 与健康对照组相比,使用的BD患者评估甲状腺体体积和回声性.
- 探索甲状腺变化,临床变量和使用者的甲状腺功能之间的关联.
主要方法:
- 这是一项对102名参与者的观察研究 (52名BD患者服用,50名健康对照).
- 评估包括临床秤,甲状腺功能测试,抗TPO抗体,血清水平和甲状腺超声波.
主要成果:
- 服用的BD患者的甲状腺体体积明显大于对照组 (10.67 ± 5.46毫升 vs 4.30 ± 2.06毫升; p < 0.001).
- 在BD患者中观察到血清TSH升高 (p = 0.018),而抗TPO阳性是可比的.
- 甲状腺结节在男性BD患者中更为频繁 (p = 0.013).
- 甲状腺体积与TSH水平或反应没有关联 (p > 0.05).
结论:
- 在BD中使用与均的甲状腺扩大有关.
- 在这个队列中,甲状腺体积的变化与甲状腺功能或反应无关.
- 需要进一步的前性研究来了解这些甲状腺变化的长期轨迹.
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