移民和非移民的乳腺癌特异性存活率被邀请参加挪威的BreastScreen
Sameer Bhargava1, Jonas Gjesvik2, Jonas Thy2
1Department of Oncology, Akershus University Hospital, Lørenskog, Norway.
Journal of migration and health
|September 12, 2024
概括
尽管非西方移民有先进的瘤特征,但乳腺癌存活率与非移民相似. 这表明,即使对查的机会不平等,也可以通过适当的随访和治疗实现公平的结果.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 与非移民相比,移民在BreastScreen Norway的出席率较低.
- 非西方移民的乳腺癌发病率较低,但疾病更为晚期.
研究的目的:
- 为了比较移民和非移民之间的乳腺癌特异性生存率.
- 根据癌症检测模式 (屏幕检测与症状) 分析生存率.
主要方法:
- 在挪威对28320名年龄在50-69岁的女性进行了分析,诊断出患有乳腺癌.
- 根据移民身份 (非移民,西方,非西方) 和检测方式的分层.
- 考克斯回归建模以评估生存差异.
主要成果:
- 非西方移民的查检测的癌症显示,与非移民 (21.3%) 相比,组织学三级癌症的发病率更高 (28.7%).
- 在非西方移民中,在查之外检测到的癌症更大,更先进 (更高等级,淋巴结阳性).
- 对乳腺癌死亡的调整后危险比率没有显示移民群体和非移民群体之间的统计学上显著差异.
结论:
- 在移民群体和非移民群体之间没有观察到乳腺癌特异性生存率的统计学上显著差异.
- 尽管非西方移民的瘤特征更为先进,但公平的生存率表明了随访和治疗的有效性.
- 需要进一步的研究,考虑到潜在的生存率高估和低事件数量.
相关概念视频
Cancer Survival Analysis
334
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
334
Comparing the Survival Analysis of Two or More Groups
162
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
162


