在早产婴儿的血液动力学上显著的专利管道动脉关闭装置
Alban-Elouen Baruteau1,2,3,4, Mathilde Méot5, Nadir Benbrik1
1Department of Pediatric Cardiology and Pediatric Cardiac Surgery, Nantes Université, CHU Nantes, FHU PreciCare, Nantes, France.
JACC. Advances
|September 12, 2024
概括
在早产婴儿的专利导管动脉 (PDA) 是常见的. 用Amplatzer Piccolo Occluder关闭透导管为符合条件的婴儿提供了一种安全有效的替代手术方案.
科学领域:
- 新生儿心脏病学 新生儿心脏病学
- 儿科干预心脏病学
- 新生儿手术 新生儿手术
背景情况:
- 专利性动脉管 (PDA) 是早产婴儿的常见并发症,显著增加了发病率和死亡率.
- 目前对血液动力学显著的PDA的管理策略缺乏共识,尽管有许多试验.
- 对PDA的药物治疗具有有限的疗效和严重不良事件的潜力.
研究的目的:
- 审查通过导管PDA关闭的患者选择标准.
- 为安普拉特泽皮科罗封闭器提供一个程序指南.
- 为了评估超导管PDA关闭在极低出生体重的婴儿的结果.
主要方法:
- 对通过导管PDA关闭的患者选择的审查.
- 用Amplatzer Piccolo Occluder使用的逐步程序描述.
- 对跨导管PDA关闭的结果数据的全面分析.
主要成果:
- 用AMPLATZER Piccolo Occluder关闭穿导管是一个安全有效的选择,适合适龄婴儿.
- 这种方法越来越多地被接受,作为外科绑架的替代方案.
- 在700克以上的出生体重极低的婴儿中,成功关闭被证明是成功的.
结论:
- 过导管关闭是一种可行的,有效的治疗,在早产婴儿的专利管道动脉.
- 阿姆普拉特泽Piccolo Occluder可以帮助安全有效地关闭PDA.
- 这种最少的侵入性技术改善了脆弱新生儿的结果.
相关概念视频
Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Fetal Circulation
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...


