慢性鼻炎和心理健康
Najm S Khan1, Meher Gajula2, Lexi Goehring3
1Department of Otolaryngology-Head and Neck Surgery, Houston Methodist Hospital, Houston, Texas.
JAMA otolaryngology-- head & neck surgery
|September 12, 2024
概括
慢性鼻炎 (CRS) 显著增加患焦虑和抑郁症的风险. 相反,焦虑和抑郁也会增加患上CRS的可能性,这表明双向关系.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 慢性鼻炎 (CRS) 越来越多地被认为与精神健康状况有关.
- 需要进一步研究CRS,焦虑和抑郁之间的相互作用,特别是关于社会经济因素和时间性.
研究的目的:
- 调查慢性鼻炎 (CRS) 与焦虑和抑郁的发展之间的双向风险.
主要方法:
- 一项回顾性队列研究利用了国家卫生研究院"我们所有人"数据库 (2008-2018).
- 成年患者的倾向性得分与年龄,性别,种族和收入相匹配 (1:5),比较有和没有CRS的患者.
- 多变量逻辑回归和生存分析评估了焦虑和抑郁症发展的主要结果以及发展CRS的风险.
主要成果:
- 患有CRS的患者患有焦虑症 (OR,4.39) 和抑郁症 (OR,2.04) 的几率显著增加.
- 患有CRS的人面临患有焦虑症 (HR, 2.79) 和抑郁症 (HR, 1.40) 的风险增加.
- 相反,患有焦虑或抑郁症的患者患有CRS的风险增加 (HR分别为2.37和1.59).
结论:
- 慢性鼻炎和常见的精神疾病,如焦虑和抑郁症之间存在显著的双向关联.
- 医疗保健提供者应该意识到这种联系,并为患有CRS,焦虑或抑郁症的患者实施适当的查.
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