Markus Diefenhardt1,2, Daniel Martin1,3,2, Ralf-Dieter Hofheinz4

  • 1Goethe-University Frankfurt, University Hospital, Department of Radiotherapy, Frankfurt, Germany.

JAMA network open
|September 12, 2024
PubMed
概括

在新辅助治疗后,持续的淋巴结转移 (PLNM) 表明直肠癌患者的预后不佳. 总的新辅助治疗 (TNT) 显著减少了ypN2阶段,为改善这些高风险患者的治疗结果提供了潜在的策略.

相关概念视频

Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...