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Updated: May 10, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Published on: May 6, 2019

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一个第1阶段的CD40激动剂MEDI5083与杜尔瓦卢马布结合在患有晚期固体瘤的患者中进行的研究

Ben Tran1, Mark Voskoboynik2,3, Johanna Bendell4

  • 1Peter MacCallum Cancer Centre, Melbourne, 8006, Australia.

Immunotherapy
|September 12, 2024
PubMed
概括

与杜尔瓦卢马布 (durvalumab) 结合的第一个CD40agonistMEDI5083的人类试验显示了显著的注射部位反应和毒性,限制了MEDI5083在先进的固体瘤中的进一步发展.

关键词:
CD40 CD40 CD40 CD40 CD40 CD40 CD40 CD40 CD40 CD40 CD40 CD40在CD40L中,CD40L是CD40L.癌症 癌症 癌症 癌症 癌症有效性 有效性 有效性.融合蛋白质是融合蛋白质的组成部分.在安全方面,安全是安全的.

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