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消除脊髓灰质炎的进展 - 巴基斯坦,2023年1月至2024年6月

Chukwuma Mbaeyi, Anwaar Ul Haq, Rana Muhammad Safdar

MMWR. Morbidity and mortality weekly report

|September 12, 2024

概括

野生1型脊髓灰质炎病毒 (WPV1) 传播在巴基斯坦持续,在2023-2024年增加病例和环境检测. 打断WPV1需要持续的承诺和应对疫苗接种挑战.

科学领域:

流行病学流行病学
公共卫生公共卫生
传染病控制和控制传染病

背景情况:

全球脊髓灰质炎根除倡议在全球范围内显著减少了野生脊髓灰质炎病毒 (WPV).
野生小儿麻病毒1型 (WPV1) 传播目前仅限于阿富汗和巴基斯坦.
由于复杂的社会政治和安全因素,巴基斯坦在根除WPV1方面面临着持续的挑战.

研究的目的:

评估巴基斯坦野生1型脊髓灰质炎病毒 (WPV1) 传播的现状.
确定阻碍巴基斯坦脊髓灰质炎根除工作的挑战.
建议用于中断WPV1传输的策略.

主要方法:

分析了巴基斯坦报告的WPV1病例.
对WPV1.1的环境监测数据 (污水样本) 的审查.
评估社会政治和安全因素对消除脊髓灰质炎的影响.

主要成果:

截至6月30日,巴基斯坦在2024年报告了8起WPV1病例,超过了2023年全部的6起病例.
在2023-2024年检测到300多个WPV1阳性环境样本.
在卡拉奇,佩沙瓦和奎达观察到WPV1的广泛传播.

结论:

巴基斯坦目前并没有打破WPV1传播的轨道.
持续的政治承诺和问责对消除脊髓灰质炎至关重要.
需要加大努力来接触错过的儿童,并解决疫苗犹和社区抵抗.

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