白质的断开会影响中风后的自身感受
Matthew Chilvers1,2, Trevor Low1,2, Deepthi Rajashekar1,2
1Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
PloS one
|September 12, 2024
概括
卒中幸存者经常经历自身感知障碍. 这项研究表明,对特定白质道的损伤,包括上纵和弧形,显著影响了中风后的手臂位置匹配性能.
科学领域:
- 神经科学是一个神经科学.
- 神经康复疗法 神经康复疗法
- 白色物质通过白色物质的轨迹.
背景情况:
- 自身感知障碍影响50-64%的中风幸存者.
- 了解白质在中风后自身感受中的作用是有限的.
- 行为缺陷往往源于大脑网络断开的连接.
研究的目的:
- 调查中风后与自身感知缺陷相关的白质脱节.
- 为了识别与手臂位置匹配受损相关的特定白质道.
主要方法:
- 评估了203名中风幸存者的机器人手臂位置匹配 (APM) 任务上的白质病变负荷和性能.
- 使用神经成像和机器人评估,大约在中风后2周.
- 研究了APM障碍和没有APM障碍的参与者之间的脱节差异.
主要成果:
- 上部纵向囊 (SLF II和III),弧形囊和正面岛屿通道的损伤负荷增加与较差的APM性能相关.
- 患有APM损伤的参与者在体后部,下面的前后囊,下面的纵向囊和光学辐射中表现出额外的断裂.
结论:
- 在中风后的自感性处理中,白质网络至关重要.
- 除了传统途径之外,确定了关键的白质通道,参与从头顶和额头部区域传递自身感知信息.
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