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Updated: Jun 13, 2025

Immunostaining-Based Detection of Dynamic Alterations in Red Blood Cell Proteins
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激活酸激酶可以通过减少3带氨酸酸化,改善红细胞的完整性

Kang Le1, Xunde Wang1, Jonathan Chu2

  • 1Laboratory of Sickle Cell Genetics and Pathophysiology, Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.

Blood advances
|September 12, 2024
PubMed
概括

在状细胞疾病 (SCD) 中使用AG-348激活酸盐激酶 (PK) 会增加红细胞ATP,改善血红蛋白水平和生存率. 这些好处在停止治疗后仍然存在,这表明可行的抗治疗.

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