在中期复发性复发性多发性硬化症患者中,与疾病相关的感知不确定性
Julia Sabin1, Elisa Salas2, Jesús Martín-Martínez3
1Department of Neurology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Multiple sclerosis and related disorders
|September 12, 2024
概括
与疾病相关的不确定性在中期复发性复发性多发性硬化症 (RRMS) 中很常见. 了解不确定性因素可以帮助制定终身患者应对多发性硬化症的策略.
科学领域:
- 神经学 神经学
- 心理学 心理学 心理学
背景情况:
- 多发性硬化症 (MS) 呈现出可变的疾病过程,往往导致残疾和生产力下降.
- 患有多发性硬化症的患者由于疾病进展不可预测,在管理他们的病情方面遇到挑战.
研究的目的:
- 在初始诊断阶段以外,评估复发性复发性多发性硬化症 (RRMS) 患者的疾病相关不确定性.
- 确定与中期RRMS患者与疾病相关的不确定性相关的因素.
主要方法:
- 进行了一项多中心的非干预性研究.
- 包括被诊断患有RRMS的患者 (2017年麦当劳标准) 疾病持续时间为3-8年.
- 使用米歇尔疾病不确定性尺度 (MUIS) 测量不确定性;使用斯皮尔曼等级相关性分析关联.
主要成果:
- 研究了201名患者 (平均年龄38.7岁,女性71.4%).
- 感知不确定性与疲劳,症状严重程度,焦虑,抑郁和威胁疾病的感知有积极的相关性.
- 不确定性与自我管理,自我有效性,处理速度,MS知识和生活质量有负相关性.
结论:
- 与疾病相关的不确定性在中期RRMS中普遍存在.
- 识别不确定性及其相关因素对于制定预防策略至关重要.
- 这些策略可以帮助患者终身应对多发性硬化症.
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