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2019年冠状病毒疾病与儿童神经疾病之间的关联强度:一项病例对照研究

Utcharee Intusoma¹, Wisarut Srisintorn², Titaporn Thamcharoenvipas¹

¹Division of Neurology, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

Neuroepidemiology

|September 12, 2024

概括

这项研究发现了COVID-19和儿童的神经疾病,特别是中风之间的联系. 这项研究强调了在流行病期间监测儿科神经健康的重要性.

科学领域:

儿科神经学儿科神经学
传染病流行病学传染病流行病学
公共卫生公共卫生

背景情况:

在成年COVID-19病例中,神经系统并发症被认可.
有限的数据存在于COVID-19和儿科神经系统疾病 (NDs) 之间的关联.
了解这些联系对于在流行病期间管理儿童健康至关重要.

研究的目的:

在COVID-19大流行期间调查儿童NDs的时间趋势.
评估COVID-19感染与儿科人口中NDs发生率之间的关联.
为了确定可能与最近或同时出现的COVID-19相关的特定的ND.

主要方法:

分析泰国国家住院数据 (2017-2022年) 对于特定NDs的18岁以下儿童.
间断时间序列分析以检测发生率趋势的变化后流行病声明.
匹配的病例控制研究使用后勤回归来评估COVID-19与NDs的关联.

主要成果:

在COVID-19第三波期间,观察到视神经炎发病率显著增加.
患有ND的儿童最近/同时患有COVID-19的患病率更高 (aOR:1.95).
儿科中风与最近/同时出现的COVID-19有显著的关联 (aOR:3.05).

结论:

最近或同时感染COVID-19与儿童神经系统疾病风险增加有关.
儿科中风是与COVID-19相关的关键神经疾病之一.
研究结果强调,需要对COVID-19感染后儿童的神经复发症保持警.

关键词:

在 COVID-19 疫情中,案例控制研究研究.神经系统疾病神经系统疾病视神经炎是一种视神经炎.一次性中风,中风.

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