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在以家庭为中心的生活方式干预中治疗肥胖儿童的BMI的长期变化
Rasmus Møller Jørgensen1,2,3,4, Henrik Støvring1,5, Jane Nautrup Østergaard1
1Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Obesity facts
|September 12, 2024
概括
这项关于儿童肥胖干预的研究发现,虽然一个计划显示了适度的,持续的BMIz-score降低,但这两项干预都没有证明长期有效. 为了更有影响力的肥胖治疗,需要进一步的研究.
科学领域:
- 儿科 儿科 儿科
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 儿童肥胖症需要进行长期干预评估.
- 之前的研究往往缺乏延长后续期.
- 这项研究解决了对儿童肥胖生活方式干预的长期数据的需求.
研究的目的:
- 为了研究肥胖儿童的长期体重增加.
- 为了比较两个务实的,以家庭为中心的生活方式干预措施.
- 评估干预措施在两年以后的持续影响.
主要方法:
- 2010年至2020年,对丹麦儿童 (4-17岁) 患有肥胖的观察性研究.
- 来自两个社区干预 (阿尔胡斯和兰德斯) 的数据与国家登记处的数据合并.
- 调整后的混合效应模型分析了身体质量指数 (BMI) z-score 的变化,并进行了子组和效应修改分析.
主要成果:
- 703名干预参与者和2,337名非参与者的中位随访时间为2.8年.
- 这两种干预措施最初都降低了BMI z-score,但只有兰德斯干预措施持续减少 (-0.05 SD/年).
- 较低的家庭收入,移民背景和1年以下的干预与BMI z-score的增加有关.
结论:
- 一个动态的,更长时间的干预措施实现了适度的,持续的BMIz-score降低.
- 这些干预措施的临床影响可能对肥胖儿童的长期有益的BMI发展有限.
- 有效性各不相同,某些子组显示出不太有利的结果.
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