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Updated: Jun 13, 2025

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Bcl-xL通过CtBP2转移到细胞核,以表观遗传促进转移

Tiantian Zhang1, Sha Li1, Yingcai Adrian Tan2

  • 1Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, 10065, USA.

Cancer letters
|September 12, 2024
PubMed
概括

核Bcl-xL通过与CtBP2和MLL1相互作用,促进癌症转移,从而导致基因修饰和基因上调. 这种相互作用为Bcl-xL过度表达的癌症提供了新的治疗点.

关键词:
在 Bcl-xL 中.在CtBP2中使用.表观遗传修饰是一种表观遗传修饰.H3K4me3是什么意思 H3K4me3是什么意思转移 转移 转移 转移

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