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先天性脑瘤:手术结果和长期预后因素

Ahmet Ilkay Isikay¹, Muhammet Enes Gurses¹, Neslihan Nisa Gecici¹

¹Department of Neurosurgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

World neurosurgery

|September 12, 2024

概括

手术切除对于婴儿先天性脑瘤 (CBT) 来说至关重要. 然而,尽管进行了积极的治疗,高度恶性瘤的预后仍然不佳,这凸显了改善治疗策略的必要性.

科学领域:

儿科神经外科儿科神经外科
在瘤学瘤学.
在先天性神经病理学.

背景情况:

先天性脑瘤 (CBT) 很少见,在婴儿管理方面存在重大挑战.
婴儿中CBT的长期结果和预后因素尚未确定.

研究的目的:

评估一岁以下婴儿CBT手术干预的长期结果.
确定影响这一儿科患者生存率的关键因素.

主要方法:

对70名接受CBT总体或次总体切除的婴儿 (2001-2019) 的回顾性分析.
包括人口,临床和瘤特征数据,包括脑水和辅助疗法.
考克斯回归分析以确定生存预测因素.

主要成果:

总体而言,5年和10年生存率分别为78%和63%.
高度瘤,手术前水头,较大的瘤大小,以及心室关节突变装置的放置与降低的生存率有关.
瘤等级和大小独立地预测了不良预后.

结论:

婴儿CBT的手术切除是必不可少的,但恶性瘤的长期结果不好.
在长期幸存者中,神经系统的后遗症很常见,强调需要全面的护理.

关键词:

大脑瘤是什么?这是一种先天性.婴儿婴儿婴儿婴儿婴儿婴儿结果结果的结果.手术手术手术整体切除整体切除

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