恶性瘤的病理特征呈现为不对称性在乳房镜上
Mohamed M H Kahila1, Allyson L Chesebro2, Catherine S Giess2
1Department of Pathology, Yale University, New Haven, Connecticut; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
概括
乳房镜检测出异对称的恶性瘤很少见,但可以呈现出微妙的透特征. 病理学家应该在核心针活检中识别这些微妙的迹象,以准确诊断.
科学领域:
- 放射学和病理学 放射学和病理学
- 在瘤学瘤学.
- 乳腺癌研究研究 乳腺癌研究
背景情况:
- 大多数乳腺癌在乳房影像上都以密集的质量出现,边界明确.
- 呈现为不对称的癌症并不常见,关于其病理特征的公布数据有限.
研究的目的:
- 为了识别在乳房镜上呈现为不对称的恶性瘤.
- 描述这些癌症的组织学和生物特征.
- 为了将这些特征与它们的乳房图形外观相关联.
主要方法:
- 追溯案例系列分析.
- 在7.5年的时间里,对18,419个核心针活检进行了审查.
- 42种呈现为不对称的恶性瘤的识别和表征.
主要成果:
- 呈现为不对称的恶性瘤占核心针活检的0.2%.
- 侵袭性癌症 (71%) 是最常见的,其次是管道癌 in situ (21%) 和淋巴瘤 (7%).
- 具有多个入侵焦点的侵袭性癌症显示了更高的淋巴结转移率和晚期.
结论:
- 病理学家必须认识到癌症的微妙透模式呈现为不对称性.
- 活检上的这些微妙特征可以反映成像的外观,帮助诊断.
- 了解这些特征对于准确解释乳房摄影不对称性至关重要.
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