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相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Aging01:26

Aging

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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Language and Cognition01:27

Language and Cognition

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Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
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Role of Cerebellum and Prefrontal Cortex in Memory01:14

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The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
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Organization of the Brain01:30

Organization of the Brain

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The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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相关实验视频

Updated: Jun 13, 2025

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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在正常衰老和认知中大脑结构-功能合之间的关系:一个跨种族基于人口的研究.

Chang Liu1, Jing Jing2, Jiyang Jiang3

  • 1Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.

NeuroImage
|September 12, 2024
PubMed
概括

随着年龄的增长,大脑结构-功能合会减弱,影响认知功能. 这项研究引入了一个新的指数来测量这种合,提供了对老化大脑机制和神经疾病潜在早期诊断的见解.

关键词:
大脑机制的大脑机制认知能力 认知能力 认知能力结构功能合 结构功能合

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相关实验视频

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科学领域:

  • 神经科学是一个神经科学.
  • 脑部成像 脑部成像
  • 认知老龄化 认知老龄化

背景情况:

  • 了解大脑结构和功能如何相互作用,对于解释认知行为至关重要.
  • 老化大脑中的结构功能合的精确性质在很大程度上是未知的.

研究的目的:

  • 开发和验证一个新的索引,脑结构连接体和功能连接体 (C-BSF) 索引的合.
  • 量化老龄化个体的区域结构-功能合.
  • 研究结构-功能合,年龄和认知表现之间的关系.

主要方法:

  • 使用的扩散张力成像 (DTI) 和静止状态功能磁共振成像 (fMRI) 数据.
  • 分析了来自两个大型队列的数据:PRECISE研究 (n=2007) 和MAS队列 (n=254).
  • 计算了C-BSF指数,以评估不同大脑网络的结构-功能合.

主要成果:

  • 结构-功能合在大脑网络中各不相同,在视觉网络中最强,在腹部注意力网络中最弱.
  • 较弱的结构功能合与晚年和较差的认知状态相关.
  • 视觉网络中的合减少与视觉空间性能有关,并部分解释了年龄对视觉空间功能的影响.

结论:

  • C-BSF指数为评估老化中的大脑结构功能完整性提供了有价值的指标.
  • 衰老与大脑结构功能合的减弱有关,导致认知能力下降.
  • 这些发现可以为与年龄相关的神经疾病的早期诊断和治疗策略提供信息.