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Updated: Jun 13, 2025

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
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In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

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通过结合性先天免疫疗法绕过尤文肉瘤微环境中的抗性

Wen Luo1,2, Hai Hoang1, Hongwen Zhu1

  • 1Department of Pediatrics, New York Medical College, Valhalla, New York, USA.

Journal for immunotherapy of cancer
|September 12, 2024
PubMed
概括

这项研究表明,在临床前模型中,将向MCAM的CAR-NK细胞与IL-15和CD47阻断组合起来,可以有效地治疗转移性尤宁肉瘤. 这种免疫疗法方法为生存选择有限的患者提供了新的希望.

关键词:
化学抗原受体 - - CAR巨细胞是一个巨细胞.自然杀手 - - NK - - 是一种自然杀手.瘤微环境 - - 瘤微环境

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