来自澳大利亚免疫受损患者的样本的临床注释生物存储的协议,以调查宿主微生物群相互作用
Olivia C Smibert1,2,3,4,5,6, Jason A Trubiano4,5,6,7, Jason C Kwong4,8
1Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia oliviasmibert@gmail.com.
BMJ open
|September 12, 2024
概括
这项研究建立了一个生物存储库来研究肠道微生物群.
科学领域:
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 人的肠道微生物群影响疾病的结果,很可能是通过免疫系统的相互作用.
- 了解这些相互作用对于免疫功能受损的患者至关重要.
研究的目的:
- 建立来自不同患者群体的临床注释样本的生物存储库.
- 探索肠道微生物群和免疫系统在免疫功能受损的个体之间的相关性.
- 确定微生物组相关的不良健康结果的风险因素.
主要方法:
- 在澳大利亚三个中心收集对血和微生物群 (便,唾液) 样本.
- 从急性白血病,肝病,接受免疫治疗,已故器官捐献者和健康对照患者的纵向和一次性点取样.
- 在日常护理过程中采集支气管支气管洗液和组织活检.
主要成果:
- N/A - 这是建立生物存储库的协议.
结论:
- N/A - 这是建立生物存储库的协议.
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