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采用APTAMER调节的体外转录的Plug-and-play蛋白质生物传感器

Heonjoon Lee1, Tian Xie2, Byunghwa Kang3

  • 1Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Nature communications
|September 12, 2024
PubMed
概括

研究人员开发了一种新的aptamer调节的转录平台,用于创建可编程分子生物传感器. 这种创新方法使蛋白质生物传感器的模块化设计能够用于各种研究和生物技术应用.

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Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
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