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Updated: Jun 13, 2025

An Efficient Strategy for Generating Tissue-specific Binary Transcription Systems in Drosophila by Genome Editing
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Published on: September 19, 2018

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在Drosophila melanogaster中扩展CRISPR基编辑工具箱

Michael Clark1, Christina Nguyen2, Hung Nguyen1

  • 1Applied BioSciences, Macquarie University, Sydney, NSW, Australia.

Communications biology
|September 12, 2024
PubMed
概括

克里斯普尔细胞因子基编辑器 (CBEs) 在果中实现了高的DNA编辑率. 促进者选择和性别特异性传播是有效基准编辑的关键,使昆虫遗传生物控制等应用成为可能.

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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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