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Updated: Jun 13, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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固体瘤诱导的系统性免疫抑制涉及二分化的骨髓状B细胞相互作用

Xiaoxin Hao1,2,3,4, Yichao Shen1,2,4,5,6, Jun Liu1,2,5

  • 1Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA.

Nature cell biology
|September 12, 2024
PubMed
概括

固体瘤会导致免疫抑制,影响髓状细胞和T细胞. 这项研究确定了两种瘤诱导的B细胞异常 (TiBA) 模式,即TiBA-1和TiBA-2,与骨髓变化有关,并可能指导定制的癌症免疫疗法.

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