相关实验视频

Updated: Jun 13, 2025

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

在以价值为基础的条件下深化帕金森病患者的决策过程:一项比较研究

Laura Colautti¹, Paola Iannello², Maria Caterina Silveri²

¹Department of Psychology, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 1, 20123, Milan, Italy. laura.colautti1@unicatt.it.

Cognitive, affective & behavioral neuroscience

|September 12, 2024

概括

帕金森病 (PD) 患者因大脑变化和药物治疗而做出更有风险的决定. 执行职能和个体特征也影响这些选择,影响临床护理.

科学领域:

神经科学是一个神经科学.
认知心理学认知心理学
临床神经学临床神经学

背景情况:

帕金森病 (PD) 与改变决策 (DM) 有关,可能是由于神经退行和多巴胺药物治疗.
关于PD和风险选择的现有研究是有限的和混合的,特别是当排除冲动控制障碍时.
执行职能 (EF) 的作用和与PD相关的DM中的个人差异仍然未得到充分研究.

研究的目的:

在没有冲动控制障碍的帕金森病患者中,以价值为基础的决策 (DM) 与健康对照进行比较.
检查决策能力,执行功能 (EFs) 和多巴胺类药物治疗PD患者的个体差异之间的关系.

主要方法:

基于价值的DM,认知能力 (EF) 和个体差异在33名PD患者和33名匹配的对照中进行了评估.
另一组42名服用多巴胺作用药物的PD患者接受了类似的评估.
使用非参数统计分析来评估群体差异和关系.

主要成果:

与健康对照组相比,PD患者的决策风险较高,受到情境因素的影响.
在PD患者中,风险选择的数量与多巴胺药物剂量,EF和个体差异有显著的相关性.

结论:

帕金森病患者,即使没有冲动控制障碍,也表现出基于价值的决策改变.
执行职能和个体差异,以及药物治疗,是影响PD风险选择的关键因素.
研究结果表明,潜在的临床干预措施针对PD管理中的认知和个体因素.

关键词:

决策决策是做出决定的.多巴胺是一种多巴胺.执行职能执行职能执行职能游戏的子任务任务.爱荷华州的博任务帕金森病是帕金森氏症的一种疾病.

更多相关视频

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

Published on: May 31, 2016

相关概念视频

Parkinson's Disease: Treatment

Parkinson's Disease: Treatment

Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...

Parkinson's Disease: Overview

Parkinson's Disease: Overview

Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...

Neural Regulation

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.

Patient-centered Care

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...