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Updated: Jun 13, 2025

Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes
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仅c-Myc就足以将纤维细胞重新编程成功能性巨细胞

Shanshan Li1, Guoyu Chen2, Xia Huang1

  • 1Pediatric Translational Medicine Institute, Department of Hematology & Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.

Journal of hematology & oncology
|September 12, 2024
PubMed
概括

使用c-Myc过度表达重新编程纤维细胞成为功能性巨细胞,为癌症免疫治疗提供了一种新的策略. 这种方法产生"现成"的巨细胞,克服了固体瘤细胞治疗方面的挑战.

关键词:
纤维母细胞细胞是如何形成的免疫治疗是一种免疫疗法.巨细胞是一个巨细胞.重编程 重编程 是一种重编程.c-Myccc 的意思是我的

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