相关实验视频

Updated: Jun 13, 2025

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
07:26

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Published on: January 31, 2025

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SIK2:FGF2信号传输的一个新型负反调节器

Gamze Kuser-Abali1,2, Asli Ugurlu-Bayarslan1,3, Yeliz Yilmaz1,4

  • 1Department of Molecular Biology and Genetics, Bogazici University, Bebek, Istanbul, 34342, Turkey.

Advanced biology
|September 13, 2024
PubMed
概括

纤维细胞生长因子2 (FGF2) 通过Ras/ERK1/2通路触发细胞增殖. 这项研究揭示了盐诱导酶2 (SIK2) 作为负反调节剂,酸化Gab1以抑制FGF2诱导的增殖.

关键词:
在FGF2信号传输中.在 Ras/ERK1/2 路径中.这就是SIK2的意义.控制细胞增殖的控制.

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