定义变更和更新临床指南的间歇性囊炎和膀疼痛综合征
Yukio Homma1, Yoshiyuki Akiyama2, Jang Hwan Kim3
1Department of Interstitial Cystitis Medicine, Kyorin University, Mitaka, Japan.
Lower urinary tract symptoms
|September 13, 2024
概括
间歇性囊炎 (IC) 和膀疼痛综合征 (BPS) 是不同的疾病,有不同的原因和治疗方法. 区分IC和BPS对于有效管理过敏膀症状至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 免疫学 免疫学 免疫学
- 病理学 病理学 病理学
背景情况:
- 间歇性囊炎 (IC) 和膀疼痛综合征 (BPS) 与类似的过敏膀 (HSB) 症状.
- 以前的指南没有充分区分IC和BPS.
- 了解不同的病理生理学和组织病理学对于准确的诊断和治疗至关重要.
研究的目的:
- 修订IC和BPS的临床指南.
- 将IC和BPS明确定义为独立的实体.
- 建立基于差异诊断的诊断和管理算法.
主要方法:
- 审查和更新以前的临床指南.
- 基于亨纳病变,炎症和HSB症状的IC定义.
- 基于HSB症状的BPS定义,没有亨纳病变或其他可混的疾病.
- 强调通过囊镜对差异诊断来识别亨纳病变.
主要成果:
- IC的特点是免疫性炎症,自身免疫性,严重的膀炎症,血细胞透和泌尿器脱皮.
- BPS涉及多因素原因,包括神经性炎症,泌尿器缺陷和神经过活性,病理变化最小.
- 截然不同的病理生理学和病理学特征使IC与BPS区分开来.
结论:
- IC和BPS是单独的疾病,需要不同的诊断和治疗方法.
- 囊镜对于通过识别汉纳病变来区分IC和BPS至关重要.
- 应根据IC或BPS的具体诊断实施量身定制的管理策略,同时分享共同的疼痛管理原则.
相关概念视频
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
147
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
147
Drugs for Treatment of Constipation-Predominant IBS
145
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
145
Irritable Bowel Syndrome III: Medical and Nursing Management
180
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
180
Drugs for Treatment of Diarrhea-Predominant IBS
153
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
153
Irritable Bowel Syndrome I: Introduction
257
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
257
Chronic Bowel Disorders: Introduction
410
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
410


