雄激素脱发与较严重的下尿道症状有关,这是良性前列腺增生症的次要症状
Yasar Pazir1, Mustafa Kadihasanoglu2
1Department of Urology, Haseki Training and Research Hospital, Istanbul, Turkey.
Lower urinary tract symptoms
|September 13, 2024
概括
患有雄激素脱发症 (AGA) 的男性由于良性前列腺增生症 (BPH) 而经历更严重的下泌尿道症状 (LUTS). 较高的丸激素水平和AGA严重程度与增加的LUTS相关,特别是储存症状和夜.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 皮肤病学 皮肤病学
背景情况:
- 雄激素性脱发症 (AGA) 是老年男性常见的疾病.
- 良性前列腺增生 (BPH) 的次要下尿道症状 (LUTS) 也随着年龄的增长而增加.
- AGA与LUTS/BPH之间的潜在关联需要进一步调查.
研究的目的:
- 在患有良性前列腺增生症 (BPH) 的患者中,调查雄激素脱发 (AGA) 和下泌尿道症状 (LUTS) 之间的关联.
- 为了比较患有和没有AGA的患者之间的临床和泌尿动力学参数.
- 探索AGA严重程度,水平和LUTS严重程度之间的相关性.
主要方法:
- 对148名45岁以上的男性患者进行了前性研究,这些患者患有BPH继发的LUTS.
- 根据诺伍德-汉密尔顿分类,患者被分为雄激素脱发症 (AGA) (n=69) 和非AGA (n=79) 组.
- 评估包括国际前列腺症状评分 (IPSS),尿液流量计,前列腺体积,血清总 (TT) 和前列腺特异性抗原 (PSA).
主要成果:
- 在AGA组表现出显著更高的血清总丸激素 (TT) 水平 (p=0.01).
- 患有AGA的患者报告了显著更高的总IPSS (p=0.04),IPSS存储子评分 (IPSS-S) (p=0.03) 和更多的夜发作 (p<0.01).
- AGA等级与TT水平 (r=0.407,p=0.003),IPSS-S (r=0.164,p=0.04) 和夜尿 (r=0.203,p=0.015) 正相关.
结论:
- 雄激素性脱毛症 (AGA) 与患有良性前列腺增生症 (BPH) 的男性更严重的下泌尿道症状 (LUTS) 有关.
- 在患有AGA和LUTS/BPH的男性中观察到较高的血清总 (TT) 水平.
- AGA的严重程度与储存LUTS和夜的增加相关,这表明潜在的共同荷尔蒙或病因途径.
相关概念视频
Disorders of the Male Reproductive System
358
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
358
Menopause
146
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
146
Disorders of the Urinary System
264
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
264
Adrenergic Antagonists: Pharmacological Actions of ɑ-Receptor Blockers
559
α-Adrenergic antagonists, known as α-blockers, exert their effects by inhibiting α-adrenoceptors, leading to specific physiological actions. α1-blockers and α2-blockers have distinct pharmacological actions and therapeutic applications.
α1-blockers: These drugs inhibit α1-adrenoceptors on smooth muscle cells, resulting in vasodilation. This vasodilation lowers blood pressure, making α1-blockers valuable in treating hypertension. Additionally,...
α1-blockers: These drugs inhibit α1-adrenoceptors on smooth muscle cells, resulting in vasodilation. This vasodilation lowers blood pressure, making α1-blockers valuable in treating hypertension. Additionally,...
559
Accessory Glands of the Male Reproductive System
1.5K
The accessory ducts involved in sperm maturation and transportation include the epididymides, vasa deferentia, ejaculatory ducts, and urethra. These ducts play a critical role in the maturation, storage, and transportation of sperm from the testes to the urethra, where it is then released during ejaculation.
The epididymis is a small, comma-shaped organ located at the back of each testicle. The epididymis can be divided into three main parts: the head, body, and tail. The head of the epididymis...
The epididymis is a small, comma-shaped organ located at the back of each testicle. The epididymis can be divided into three main parts: the head, body, and tail. The head of the epididymis...
1.5K
Infertility in Males
255
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
255


