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Updated: Jun 13, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

[在阳光和阴影环境下,主要角度闭眼的眼睛前段结构和瞳孔扩张性特征的差异可疑]

M L Ma¹, J B Sun¹, H P Yuan¹

¹The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology

|September 13, 2024

概括

疑似主角闭眼 (PACS) 眼睛的动态瞳孔变化与急性主角闭眼 (APAC) 风险相关. 在PAC眼中,瞳孔平均速度 (Vm) 更慢可能表明亚太地区风险更高.

科学领域:

眼科医生眼科眼科
人体解剖学解剖学解剖学
身体生理学身体生理学

背景情况:

主要闭角光眼 (PACG) 是全球不可逆转失明的主要原因.
疑似初级角关闭 (PACS) 是PACG的前身阶段,其特点是解剖学倾向.
了解PACS眼睛的动态变化对于预测急性初级角关闭 (APAC) 事件至关重要.

研究的目的:

在不同的光线条件下调查PACS眼睛前段解剖学和动态瞳孔变化.
探索这些动态变化与亚太地区的发生之间的相关性.
在PACS患者中确定APAC的潜在预测指标.

主要方法:

涉及37名PACS患者 (66只眼睛) 的横截面研究.
超声波生物显微镜 (UBM) 用于在明暗条件下测量前段参数 (ACA,AOD,IT).
前部细分分析以记录瞳孔直径,最大扩张速度 (Vmax),最大收缩速度 (Vmin) 和平均速度 (Vm).
用于分类的暗室容易挑测试 (DRPPT).

主要成果:

在DRPPT+和APAC群体之间,UBM参数没有显著差异.
与DRPPT-组相比,APAC+组的平均瞳孔速度 (Vm) 显着较低 (P<0.05).
Vmax与时间ACA1000Δ和AOD1000Δ正相关 (P<0.05).
维敏与时间ACA1000Δ和AOD1000Δ负相关 (P<0.05).

结论:

动态瞳孔反应,特别是平均速度 (Vm),可以作为PAC患者中APAC的预测指标.
前段参数的变化与动态的瞳孔行为相关,为角度关闭机制提供了见解.
对动态变化的进一步研究可以完善亚太地区的风险分层和预防策略.

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