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辅助BcfA通过TLR4激活抗原呈现细胞,并支持TFH和TH1,同时减弱TH2基因编程

Mohamed M Shamseldin1,2,3, Kaitlin A Read1, Jesse M Hall1

  • 1Departments of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.

Frontiers in immunology
|September 13, 2024
PubMed
概括

边境菌殖民因子A (BcfA) 通过激活免疫细胞上的托尔类受体4 (TLR4) 作为辅助剂. 这种机制增强TH1/TH17反应,同时抑制TH2免疫力,改善抗原呈现.

关键词:
在 BcfAA 中.在T细胞的两极分化过程中.辅助剂 辅助剂是一种辅助剂.具有抗原的细胞呈现抗原.模式识别受体的模式识别受体

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