对手术后肺部并发症的影响 高流量鼻腔氧的频率与因癌症而接受食道切除术的患者的标准氧疗法相比:随机对照试验的研究方案-OSSIGENA研究
Cristian Deana1, Massimo Vecchiato2, Danila Azzolina3,4
1Anesthesia and Intensive Care 1, Department of Anesthesia and Intensive Care, Health Integrated Agency of Friuli Centrale, Udine, Italy.
Journal of thoracic disease
|September 13, 2024
概括
在食道切除术后,早期的高流量鼻腔管 (HFNC) 治疗没有显著减少术后肺部并发症 (PPC). 这项研究将HFNC与标准氧进行了比较,发现癌症患者的PPC率没有显著差异.
科学领域:
- 胸部外科手术 胸部外科手术
- 临界护理医学 临界护理医学
- 呼吸系统疗法 呼吸系统疗法
背景情况:
- 手术后肺部并发症 (PPC) 是食管切除术后的一个重大挑战,影响高达40%的患者.
- 尽管手术和麻醉技术取得了进展,但PPC仍然是食道切除术恢复的关键问题.
研究的目的:
- 调查早期高流量鼻管 (HFNC) 治疗在食道切除术后减少PPC频率的疗效.
- 为了比较接受HFNC和接受标准氧气治疗后输出管术的患者之间的PPC发病率.
主要方法:
- 一项随机对照试验,涉及320名患者 (每组160人),年龄在18-85岁之间,因癌症接受食道切除术.
- 随机分配患者接受HFNC或标准氧气疗法 (Venturi口罩或鼻腔管) 在输出管后48小时内.
- 主要结局是肺部并发症的发生率,包括肺炎,ARDS和再输管;进行了治疗意图分析.
主要成果:
- 最近的证据表明,HFNC改善了食道切除术后的ROX指数,但没有减少PPCs.
- 这项多中心试验专门评估了HFNC对PPC的影响,与食道切除患者的标准氧相比.
结论:
- 这项研究旨在提供关于HFNC在治疗食道切除术后患者中的作用的关键数据.
- 研究结果将为临床实践提供有关最佳氧化策略的信息,以减轻高风险人群中的肺风险.
相关概念视频
Administering Oxygen by Nasal Cannula
432
Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
432
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
187
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
187
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
408
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
408
Oxygen Delivering System I: Nasal Cannula and Face Mask
256
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
256
Administering Oxygen by Mask
263
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
263
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
178
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
178


