在正常体重的日本成年人中,对代谢异常和糖尿病风险的长度研究
Cheng Huang1, Zhichao Gao2, Yuhang Zhang3
1Department of Colorectal Surgery, First People's Hospital of Xiaoshan District, Hangzhou, Zhejiang, China.
Frontiers in endocrinology
|September 13, 2024
概括
在日本,新陈代谢不健康的正常体重 (MUNW) 个体的患病率为9.35%,糖尿病风险增加. 年轻的日本男性尤其容易受到伤害,这凸显了早期干预的必要性.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 全球糖尿病患病率正在上升,特别是在日本.
- 代谢不健康的正常体重 (MUNW) 个体面临糖尿病风险升高.
- 了解MUNW对糖尿病发病的影响对于预防至关重要.
研究的目的:
- 调查MUNW状态与非糖尿病日本成年人糖尿病风险之间的关联.
- 为了确定特定的人口群体在更高的风险.
主要方法:
- 利用了NAGALA队列中8,194名日本成年人的数据.
- 根据代谢综合征 (MetS) 组件对参与者进行分类.
- 雇员考克斯比例危险和后勤回归,按年龄和性别分层.
主要成果:
- 9.35%的参与者被归类为MUNW; 1.92%的人有MetS.
- 较高的MetS组分得分与糖尿病风险增加相关 (HRs为4.56至25.16).
- 年轻的日本男性 (≤40岁) 患糖尿病的风险最高,尤其是多个MetS组件.
结论:
- MUNW在非糖尿病的日本成年人中普遍存在,并与较高的糖尿病风险有关.
- 代谢综合征的严重程度是糖尿病发展的重要预测因素.
- 针对MUNW个体,特别是年轻男性的早期干预对于预防糖尿病至关重要.
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