在Cisatracurium和Rocuronium之间进行术后肌肉强度恢复的比较
Vidya Rani M1, Afra Farheen Faiaz1, Shanthala K Banakara2
1Department of Anesthesiology, Kanachur Institute of Medical Sciences, Mangalore, IND.
Cureus
|September 13, 2024
概括
神经肌肉阻断剂,如罗库和cisatracurium可以导致残留,影响患者的安全后麻醉. 这两种药物都显示出显著的残留化,突出显示了在麻醉后护理单位 (PACU) 进行神经刺激监测的必要性.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
背景情况:
- 神经肌肉阻断剂 (NMBA) 在麻醉中至关重要,但有风险的术后残留功能障碍.
- 在麻醉后护理单元 (PACU) 中未检测到的会危及患者的安全,增加并发症风险.
- 有效地逆转NMBAs对于预防与发病率和死亡率相关的残留术后治愈 (RPOC) 是至关重要的.
研究的目的:
- 为了比较rocuronium和cisatracurium之间残留术后化 (RPOC) 的发生率.
- 通过临床评估和外围神经刺激来评估恢复参数.
- 强调在PACU中对残留的监测的重要性.
主要方法:
- 一项涉及100名美国麻醉学会 (ASA) I和II患者的比较研究.
- 患者在麻醉期间接受了罗库或西萨特拉库.
- 使用手握,持续抬头和双爆刺激 (DBS) 抽反应来评估恢复.
主要成果:
- 两组之间没有年龄,性别,ASA身份或身体特征的显著差异.
- 恢复参数 (握手,抬头,DBS) 在罗库和西萨特拉库组之间没有统计学上显著的差异.
- 在两组中都观察到显著的残留术后治愈,每个评估方法的具体晚期恢复率为15分钟.
结论:
- 罗库和西萨特拉库都可能导致显著的残留术后化.
- 术内和PACU外周神经刺激对于准确评估神经肌肉阻塞逆转至关重要.
- 需要对手术内变量进行进一步的研究,以更好地了解和管理PACU中的残留.
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