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吸烟状态和包装年历史与尿急症症状的关联
Katharine F Michel1, Avanti N Rangnekar2, Michelle Slinger3
1Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Neurourology and urodynamics
|September 13, 2024
概括
当前吸烟显著增加了膀过活症状的风险,如急性和急性尿失禁 (UUI). 以前的吸烟没有显示这种增加的风险,这表明戒烟可能有助于管理紧急情况.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 过度活性膀 (OAB) 和急性是多因素的,吸烟被确定为可修改的危险因素.
- 之前关于吸烟和紧急情况的研究得出了不确定的结果.
- 这项研究严格评估了吸烟和急迫性之间的关联,考虑了吸烟史的时间和定量方面.
研究的目的:
- 为了评估吸烟状态和包年历史与紧急症状之间的关系.
- 确定目前或以前的吸烟以及吸烟的数量是否会影响急性和急性尿失禁 (UUI).
- 在评估吸烟与紧急情况的联系时,控制混因素.
主要方法:
- 一项针对1720名成年女性的社区在线调查评估了膀的健康状况,急性症状,并发症以及详细的吸烟史.
- 吸烟史被分析为吸烟状态 (从未,以前,目前),连续包装年和分类包装年.
- 使用多变量回归模型来控制混因素,并评估吸烟史的时间性与数量.
主要成果:
- 与从未吸烟者相比,目前吸烟者的紧急情况风险增加了23%,中等紧急情况风险增加了78%.
- 当前吸烟者急性尿失禁 (UUI) 的风险比目前吸烟者高40%.
- 20+包年病史与急性增加,中等急性和UI风险显著相关,表明剂量-反应关系.
结论:
- 目前的吸烟与女性的尿急和UUI有着强烈而一致的联系.
- 过去的吸烟状态与紧急情况风险增加没有显著关联.
- 研究结果支持将重点放在目前的吸烟上,因为它有助于紧急情况,并建议戒烟作为潜在的治疗策略.
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