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Updated: Jun 13, 2025

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与相应的原发性瘤相比,子宫内膜癌复发的组织学和分子类型变化与相应的原发性瘤相比

Esther Moreno-Moreno1,2, Tamara Caniego-Casas1,3, Irene Carretero-Barrio1,2,3

  • 1Department of Pathology.

The American journal of surgical pathology
|September 13, 2024
PubMed
概括

子宫内膜癌 (EC) 复发中的分子变化揭示了瘤进展途径. 一些低度EC获得了新的突变,特别是在PI3K/AKT/PTEN途径中,一些瘤转移了分子亚型,突出显示在复发时需要重新评估.

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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