银纳米颗粒的抗炎和抗菌活性绿色合成使用不同植物的提取物
Amr Mohamed1,2, Marwa Dayo1, Sana Alahmadi1
1Chemistry Department, College of Science, Taibah University, Al-Madinah Al-Munawarah 42353, Saudi Arabia.
Nanomaterials (Basel, Switzerland)
|September 13, 2024
概括
使用植物提取物进行银纳米粒子 (AgNPs) 的绿色合成提供了一种环保的方法. 这些AgNP表现出显著的抗炎和广泛的抗菌特性.
科学领域:
- 绿色化学 绿色化学
- 纳米技术 纳米技术
- 材料科学 材料科学 材料科学
背景情况:
- 银纳米粒子 (AgNPs) 被认为具有治疗潜力.
- 传统的合成方法可能是危险和昂贵的.
- 植物合成提供了一个可持续的替代方案.
研究的目的:
- 为AgNPs开发一种绿色生物合成方法.
- 评估AgNPs的抗炎和抗菌活性.
主要方法:
- 合成AgNP的方法是使用#Ginkgo biloba#,#Cichorium Intybus#,#Adiantum Capillus-Veneris#和#Rosmarinus Officinalis#的提取物进行合成.
- 通过UV-Vis光谱学 (SPR波段) 证实了合成.
- 使用SEM和FTIR进行表面表征;通过抑制白蛋白变质化来评估抗炎活性.
主要成果:
- 通过SPR.确认了AgNP的成功绿色合成.
- 与Meloxicam装载的AgNPs相比,装载着tenoxicam的AgNPs表现出更高的抗炎活性.
- AgNPs显示出强大的抗微生物活性,对抗阴性和阳性细菌.
结论:
- 该研究提出了一种高效,经济和环保的AgNP合成方法.
- 合成的AgNP具有有希望的抗炎和广泛的抗菌特性.
- 植物介导的AgNP是治疗应用的可行候选者.
相关概念视频
01:27Combined Effects of Drugs: Synergism
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
01:28Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...