在一个纵向队列中,戒烟和发生心房动的事件
Justin T Teraoka1, Janet J Tang1, Francesca N Delling1
1Department of Medicine, Division of Cardiology, University of California-San Francisco, San Francisco, California, USA.
JACC. Clinical electrophysiology
|September 13, 2024
概括
戒烟显著降低了患心房的风险. 这项研究发现,与目前的吸烟者相比,前吸烟者和在研究期间戒烟的人有较低的AF风险.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 吸烟是心房动 (AF) 的已知危险因素之一.
- 戒烟对AF风险的影响尚未得到充分证实.
研究的目的:
- 调查戒烟与发展心房动 (AF) 的风险之间的联系.
- 为了评估吸烟戒烟后AF风险是否可修改.
主要方法:
- 分析了146,772名英国生物库参与者与连续吸烟评估的大型纵向队列.
- 事件AF使用医疗保健接触的ICD代码进行识别.
- 考克斯的比例危险模型被用来比较当前吸烟者,前吸烟者和在研究期间戒烟者之间的AF风险,并对多个共同变量进行调整.
主要成果:
- 在平均12.7年的随访期间,11,214名参与者患有AF.
- 与目前的吸烟者相比,前吸烟者有13%的AF风险较低 (HR:0.87;95%CI:0.83-0.91).
- 在研究期间戒烟的参与者有18%的AF风险降低 (HR:0.82;95%CI:0.70-0.95).
结论:
- 戒烟与发展心房动 (AF) 的风险降低有关.
- 这些发现强调了戒烟对心血管的好处.
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