Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

645
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
645
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

1.1K
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
1.1K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.9K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

CT-guided PCI: From diagnosis to treatment planning.

Journal of cardiology·2026
Same author

CT-Guided Lipid-Lowering Therapy Leading to Functional Resolution of Ischemia.

JACC. Case reports·2025
Same author

Vessel-Specific Myocardial Mass in Patients With Stable Coronary Artery Disease.

Journal of the American Heart Association·2025
Same author

Clinical utility of coronary CT angiography to guide PCI: a survey among P4 investigators.

The international journal of cardiovascular imaging·2025
Same author

Validation of contemporary methods to assess vessel specific myocardial mass.

Cardiovascular revascularization medicine : including molecular interventions·2025
Same author

The role of advanced physiological guidance in contemporary coronary artery disease management.

Current opinion in cardiology·2024

相关实验视频

Updated: May 5, 2026

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

14.9K

在冠状动脉微血管功能障碍中进行血管重塑.

Carlos Collet1, Koshiro Sakai2, Takuya Mizukami3

  • 1Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.

JACC. Cardiovascular imaging
|September 13, 2024
PubMed
概括

患有心痛和非阻塞性冠状动脉疾病 (ANOCA) 和冠状动脉微血管功能障碍 (CMD) 的患者心上血管较小. 冠状动脉计算机断层扫描血管学 (CTA) 能够有效地检测这些患者的高微血管抵抗性.

关键词:
绝对的冠状动脉流.冠状动脉微血管功能障碍微血管阻力 微血管阻力船舶的光量体积.船舶与质量比率的比率.

更多相关视频

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

7.9K
In Vitro Model of Coronary Angiogenesis
08:03

In Vitro Model of Coronary Angiogenesis

Published on: March 10, 2020

7.7K

相关实验视频

Last Updated: May 5, 2026

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

14.9K
Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

7.9K
In Vitro Model of Coronary Angiogenesis
08:03

In Vitro Model of Coronary Angiogenesis

Published on: March 10, 2020

7.7K

科学领域:

  • 心脏病学 心脏病学
  • 血管生物学 血管生物学
  • 诊断成像 诊断成像 诊断成像

背景情况:

  • 冠状动脉微血管功能障碍 (CMD) 影响大约50%的心痛和非阻塞性冠状动脉疾病 (ANOCA) 患者.
  • 描述CMD及其相关的血管改造对于理解ANOCA至关重要.
  • 最小的微血管抵抗是评估CMD严重性的关键指标.

研究的目的:

  • 在ANOCA患者中测量最小的微血管抵抗.
  • 为了研究与最小微血管抵抗相关的血管重塑模式.
  • 评估冠状动脉计算机断层扫描血管学 (CTA) 在识别高微血管抵抗方面的诊断效用.

主要方法:

  • 对接受连续热稀释的ANOCA患者进行前性研究.
  • 使用冠状动脉CTA量化发光体积和心肌质量.
  • 冠状动脉疾病的定义 (冠状动脉流量储备<2.5) 和高最小微血管阻力 (>470 WU).

主要成果:

  • 在153名患者中,68人患有CMD;22人表现出高微血管耐药性.
  • 患有冠状动脉疾病的患者显示冠状动脉流量储备显著降低 (1.9比3.2).
  • 光量与最小的微血管抵抗有很强的相关性 (r=-0.59).
  • 患有心血管疾病和高耐药性的患者的心上膜体积比对照小40%.
  • 冠状动脉CTA表现出良好的诊断能力 (AUC=0.79),用于检测高微血管耐药性.

结论:

  • 患有CMD和高最小微血管抵抗的ANOCA患者具有较小的上心血管.
  • 冠状动脉CTA是检测ANOCA中高最小微血管电阻的宝贵工具.
  • 冠状动脉CTA可以增强ANOCA患者的诊断工作流程.