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Updated: Jun 13, 2025

Artificial Antigen Presenting Cell aAPC Mediated Activation and Expansion of Natural Killer T Cells
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CD91及其连接体gp96在对新生,新兴瘤的免疫反应中赋予多个APC交叉原始化能力

Devanshi A Nayak1, Abigail L Sedlacek1, Anthony R Cillo1,2,3

  • 1Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania.

Cancer immunology research
|September 13, 2024
PubMed
概括

树突细胞 (DCs) 上的CD91对于癌症免疫监测至关重要. 虽然CD91-表达cDC1s通过捕获gp96启动早期瘤控制,但其他DCs对于长期的瘤排斥至关重要.

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