EQ-5D-5L复合物"焦虑/抑郁"维度与大量普通人群样本中的焦虑和抑郁症状之间的性能关系
Emily Stella Scott1, Erica I Lubetkin2, Mathieu F Janssen3
1Department of Public Health, Erasmus MC, Rotterdam, The Netherlands. e.scott@erasmusmc.nl.
概括
EQ-5D-5L的焦虑/抑郁维度有效地测量了诊断组中的焦虑和抑郁症状. 然而,它的表现在年轻人中不那么准确,这表明基于年龄的比较存在潜在的缺陷.
科学领域:
- 健康 结果 研究 研究 结果
- 心理测量验证 心理测量验证
- 患者报告的结果
背景情况:
- EQ-5D-5L是广泛使用的健康状况测量仪.
- 它的焦虑/抑郁 (A/D) 维度在捕捉临床症状方面的表现需要彻底评估.
- 了解不同的人口和诊断群体的A / D维度表现对于准确的健康评估至关重要.
研究的目的:
- 评估EQ-5D-5L A/D维度与验证的焦虑/抑郁度量表 (GAD-7,PHQ-9) 之间的关系.
- 在诊断组 (焦虑,抑郁,两者,没有) 中比较A/D维度的表现.
- 调查A/D维度在人口亚组 (性别,年龄,教育,慢性疾病) 中的歧视性表现.
主要方法:
- 这是一项针对来自欧洲和美国的19902名参与者的横截面健康调查.
- 接收器运行特征曲线下的面积 (AUROC) 用于计算性能.
- 在诊断组和人口学子组之间进行了比较,并进行了敏感性分析.
主要成果:
- 在整个样本中,A/D维度显示了良好的整体性能 (AUROC>0.8).
- 诊断组之间的表现没有显著差异 (焦虑,抑郁,两者与没有).
- 根据年龄组 (年轻人更糟) 和单一慢性疾病 (焦虑/抑郁症患者更糟) 的存在,表现有显著差异.
结论:
- EQ-5D-5L A/D维度可靠地捕捉到焦虑和抑郁症的症状.
- 在年轻人群体中,表现明显较差.
- 需要进一步的研究来了解被诊断为焦虑或抑郁症患者的解释,因为与年龄相关的表现差异可能会影响年龄内比较.
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