烧伤患者的微量元素补充:探索烧伤大小和矿物质需求之间的关系
Alexander Kurjatko1, Colette Galet1, Isaac Weigel1
1Department of Surgery, Acute Care Surgery Division, University of Iowa, Iowa City, IA 52242, USA.
概括
烧伤患者的身体表面积烧伤超过22% (BSAB) 风险是缺. 早期补充是恢复的关键,特别是对于那些有较大的烧伤的人来说.
科学领域:
- 营养生物化学 营养生物化学
- 烧伤的药物烧伤的药物
- 临床营养学 临床营养学
背景情况:
- 微量元素缺乏是烧伤患者常见的并发症.
- 它可能会对伤口愈合和患者整体康复产生负面影响.
- 肠道补充是管理微量元素水平的主要策略.
研究的目的:
- 为了评估肠道微量元素补充剂的有效性.
- 为了确定关键燃烧大小,表明微量元素缺乏的风险.
- 根据烧伤严重程度指导微量元素替换策略.
主要方法:
- 从2019年8月到2022年5月,对53名烧伤患者的回顾性评估.
- 每隔2周对微量元素水平和C-反应蛋白的监测.
- 接收器运行特征 (ROC) 分析以确定缺陷风险值.
主要成果:
- 身体表面烧伤面积 (BSAB) 为22.1%的预测缺乏风险 (91.7%的灵敏度,92.6%的特异性).
- 27.5%的BSAB预测了缺铜风险 (88.9%的灵敏度,81%的特异性).
- 患有>30%BSAB的患者在2周内出现了和铜缺乏;没有发生缺乏.
结论:
- 肠道微量元素的补充是有效的预防缺陷.
- 特定的BSAB值可以预测烧伤患者的和铜缺乏的风险.
- 基于烧伤大小的早期监测和有针对性的补充剂对于最佳的患者结果至关重要.
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