在儿童和青少年患有多微症的患者中焦点扩大的周血管空间 - - 一个MRI研究
Maximilian Rauch1, Karsten Lachner2, Lea Frickel2
1Institute for Neuroradiology, Johann Wolfgang Goethe-University, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany. rauch@med.uni-frankfurt.de.
Clinical neuroradiology
|September 13, 2024
概括
在儿科患者中,在多微 (polymicrogyria,PMG) 皮层下经常发现扩大周周血管空间 (EPVS). 这一发现可能表明PMG是一种与相关的发育性脑形.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 儿科成像学 儿科成像学
背景情况:
- 多微 (Polymicrogyria,PMG) 是一种皮质形,通常与有关.
- 扩大周血管空间 (EPVS) 是血管周围充满液体的空间.
- 与PMG相关的EPVS存在需要进一步调查.
研究的目的:
- 确定PMG的儿童和青少年皮质下EPVS的频率和可见性.
- 评估EPVS作为临床MRI上PMG的潜在指标.
主要方法:
- 分析了28名患有PMG的儿科/青少年患者的MRI数据和匹配的对照.
- 在失塑皮层下检查T2加权的MR图像以检测EPVS的存在和数量 (分级0-4).
- 在考虑年龄,PMG位置和MRI场强度 (1.5T/3T) 的情况下,PMG患者和对照组之间的EPVS得分的比较.
主要成果:
- 在82% (23/28) 的PMG患者中,与异形皮质空间相关的EPVS被发现.
- 与对照组相比,PMG患者的EPVS得分显著更高,不论年龄或PMG的位置.
- 核磁共振磁场强度 (1.5T与3T) 并没有显著影响EPVS得分.
结论:
- 皮质不稳定下方的EPVS在儿科PMG患者 (82%) 中是常见的发现.
- EPVS可以作为识别PMG的有价值的成像线索.
- EPVS可能是皮质形的标志物,如PMG.
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