[多形淋巴增殖性疾病,淋巴状粒状瘤类型,在患有阳性免疫抑制的患者中,一个不寻常的实体]
Cristián Vargas1, Marcelo Abarca1, Eduardo Rojas1
1Hospital del Salvador, Universidad de Chile, Chile.
概括
免疫抑制患者面临更高的恶性瘤风险. 这一案例突出显示了一种罕见的多态B型淋巴增殖性疾病,即淋巴状粒状瘤类型的淋巴状粒状瘤,发生在免疫抑制的个体中,具有广泛的器官参与.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 病理学 病理学 病理学
背景情况:
- 患有先天性或获得性免疫缺陷的患者患恶性瘤的风险增加,特别是成熟的淋巴瘤瘤.
- 用于皮肤肌炎和抗合成酶综合征等疾病的免疫抑制疗法可以使个体易患淋巴增殖性疾病.
研究的目的:
- 报告一种罕见的多态B型淋巴扩散性疾病病例,淋巴状小粒细胞瘤类型.
- 讨论在淋巴增殖性疾病中对阳性免疫抑制的诊断挑战和影响.
主要方法:
- 一名50岁的患者的病例介绍,他有皮肤肌炎和抗合成酶综合征的病史,接受免疫抑制疗法.
- 临床评估包括活检,计算机轴心断层扫描和组织病理学分析.
- 对成熟的B型淋巴瘤的症状,组织学和当前分类的审查.
主要成果:
- 患者呈现出眼腺胀,体重减轻,夜间出汗和腹部活检后的急性腹部.
- 扫描显示了多个器官病变和一个穿孔的结肠瘤.
- 活检显示了广泛的亡与淋巴细胞透和爱斯坦-巴尔病毒 (EBV) 阳性.
结论:
- 这名患者被诊断患有多态B型淋巴扩散性疾病,淋巴状小粒细胞瘤类型.
- 这种实体不常见,很少与阳性免疫抑制有关.
- 这一案例强调了在免疫功能低下的患者中考虑淋巴扩散性疾病的重要性,这些患者有异常的表现.
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