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准备发展中国家迎接下一次大流行:来自中国新兴传染病研发蓝图的证据
Jiyan Ma1, Chao Li2, Yuxuan Cui1
1Department of Global Health, Peking University, Xueyuan Rd, No. 38, Beijing 100181, China.
Journal of infection and public health
|September 13, 2024
概括
中国制定了一项研发蓝图,以优先考虑新出现的传染病 (EID) 和医疗对策 (MCM) 以防范流行病. 这项主动战略确定了关键的病原体和技术,以加强国家应对能力.
科学领域:
- 公共卫生 公共卫生
- 传染病研究 传染病研究
- 生物安全是生物安全.
背景情况:
- 中国面临着来自特有和进口新兴传染病 (EID) 的重大威胁.
- 有效检测,预防和控制新型病毒威胁对于区域和全球卫生安全至关重要.
- 积极的规划对于减轻未来流行病影响至关重要.
研究的目的:
- 为中国新兴传染病 (EID) 建立一个研发 (R&D) 蓝图.
- 确定优先疾病和医疗应对措施 (MCMs) 以防范流行病.
- 引导积极的科学和技术行动,防止潜在的未来流行病.
主要方法:
- 利用世界卫生组织的优先级方法.
- 包含管道景观分析,快速风险评估和多维分析.
- 遵循五步过程:病原体识别,长列表,优先级,最终列表生成和研发蓝图创建.
主要成果:
- 确定了14种病毒病原体和两个病毒群 (流感HxNy,冠状病毒X) 以优先考虑MCM开发.
- 建议的国家战略库存,包括每个优先病原体的诊断,治疗和疫苗候选物.
- 突出了平台技术,以提高EID准备能力,包括研究,检测,预防,控制,监视和信息共享.
结论:
- 这是首个在低收入和中等收入国家开发的优先疾病和MCM的研发蓝图.
- 研究结果为发展中国家制定国家卫生研究议程提供了一个模型.
- 该蓝图支持预防性科学和技术策略,以应对新出现的病原体和未来的流行病.
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