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来自Polygonatum kingianum的多糖分的明显的益生菌对肠道微生物群的影响

Nan Zhang¹, Chao Zhang¹, Yu Zhang²

¹College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China; Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan 250100, China.

International journal of biological macromolecules

|September 13, 2024

概括

这项研究探讨了Polygonatum kingianum多糖分 (PKP) 分数,发现它们在消化过程中是稳定的,并调节肠道微生物群. 通过增强Bifidobacterium生长,PKP70显示出显著的益生菌潜力.

科学领域:

食品科学食品科学食品科学
生物化学生物化学
微生物学微生物学

背景情况:

植物衍生的多糖因其健康益处而越来越受认可.
了解不同多糖分的特定特性和生物活性对于它们的应用至关重要.
聚糖 Polygonatum kingianum (PKP) 是功能成分的潜在来源.

研究的目的:

为了研究PKP分量的物理化学性质,消化稳定性和体外发酵.
评估 PKP 分数对肠道微生物群组成和功能的影响.
为了确定特定的PKP分量的益生菌潜力.

主要方法:

使用等级乙醇沉来获得PKP分数 (PKP60,PKP70,PKP80).
使用染色学 (HPGPC,RPHPLC) 和尿酸分析分析了物理化学性质.
用肠道微生物群进行了体外消化和发酵试验,随后进行了微生物群分析 (β多样性,结构分析).

主要成果:

PKP分离物具有不同的分子量和单糖比例,但具有共同的三螺旋结构和中性多糖特性.
所有部分在体外消化过程中都表现出高稳定性,没有明显的降解.
肠道微生物群发酵PKP分离物,产生短链脂肪酸和调节微生物群组成,PKP70显著增强Bifidobacterium的增殖.

结论:

隔离和净化方法显著影响PKP分量的物理化学性质和生物活性.
基因基因基因分离物具有消化稳定性,并表现出益生菌效应,调节肠道微生物群.
PKP70显示出强大的益生菌潜力,突出显示了对于功能成分开发的细分特异性研究的重要性.

关键词:

我们的肠道微生物群.多边形的Kingianum多边形的Kingianum.它是一种多糖化合物.

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