在接受Impella支持的高风险PCI的二手回患者中的临床结果
Arsalan Abu-Much1, Cindy L Grines2, Shmuel Chen3
1Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA.
International journal of cardiology
|September 13, 2024
概括
尽管心力衰竭的患病率较高,但Impella支持的高风险皮肤冠状动脉干预 (HRPCI) 在患有严重腹 (MR) 的患者中没有显示出统计学上显著的较差结果.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 额叶回 (MR) 与接受皮肤冠状动脉干预 (PCI) 的患者的治疗结果较差有关.
- 评估高风险PCI (HRPCI) 患者的结局,根据MR严重程度分层的Impella支持至关重要.
研究的目的:
- 根据额头肌反 (MR) 的严重程度,评估Impella支持的HRPCI患者的结果.
- 为了确定是否严重的MR影响并发症,90天的MACCE,或1年的死亡率在这个患者群体.
主要方法:
- 从PROTECT III研究中接受Impella支持的HRPCI的患者根据MR的严重程度被分为四组.
- 评估了PCI即时并发症,90天重大心血管和脑血管不良事件 (MACCE) 和1年死亡率.
主要成果:
- 严重的MR患者的BMI,LVEF较低,心力衰竭患病率较高.
- 马上PCI并发症在MR重症组中是相似的.
- 在严重的MR患者中,未调整的90天MACCE和1年死亡率在数值上更高,但在统计学上不显著.
结论:
- 接受Impella治疗的中度/重度MR的HRPCI患者心力衰竭患病率较高,LVEF较低,住院时间较长.
- 在多变量分析中,严重的MR并没有独立预测90天MACCE或1年死亡率明显更差.
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