遗传和环境对软组织面部形状的发展的贡献:一项双胞胎研究
Jamal Giri1, Michelle Bockmann1, Alan Brook1
1Faculty of Health and Medical Sciences, Adelaide Dental School, The University of Adelaide, Adelaide, SA 5000, Australia.
European journal of orthodontics
|September 13, 2024
概括
遗传因素在混合牙和永久牙时显著影响面部形状. 在永久牙形成过程中,环境因素在下面变得更加突出,这表明对面部发育的动态影响.
科学领域:
- 人类学是人类学.
- 遗传学 遗传学 是一个
- 牙科 牙科是指牙科的专业.
背景情况:
- 面部形状的变化受到遗传和环境因素的影响.
- 了解这些影响对于正牙科和面研究至关重要.
- 双胞胎研究对于剖析复杂特征的遗传和环境贡献是有价值的.
研究的目的:
- 量化遗传和环境因素对软组织面部形状变化的相对贡献.
- 为了比较混合和永久牙阶段的这些影响.
- 为了识别具有不同病因基础的特定面部特征.
主要方法:
- 对139对双胞胎 (单胞胎和双胞胎) 的回顾性队列研究.
- 分析使用26个角度和线性测量的标准化面部形状照片.
- 单变结构方程建模用于评估附加遗传 (A),共享环境 (C) 和独特环境 (E) 的影响.
主要成果:
- 在混合牙中,添加基因 (A) 和独特的环境 (E) 解释了所有特征 (遗传率0.38-0.79).
- 在永久牙中,AE模型适合20/26的特征.
- 六个特征,特别是下面的特征,显示出共同的 (C) 和独特的 (E) 环境因素的影响增加.
结论:
- 软组织面部形状在整个发育过程中表现出动态的遗传和环境影响.
- 添加性遗传影响在混合和早期永久牙中占主导地位.
- 环境因素在永久牙的下面扮演着更大的角色,这表明了塑性.
相关概念视频
Behavioral Genetics and Its Designs
344
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
344
Gene-Environment Interactions
270
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
270
Human Genetics
547
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
The complex relationship between genetics and psychology is observable through common biological components such...
547
Polygenic Traits
65.6K
When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
65.6K
Background and Environment Affect Phenotype
6.5K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.5K
Nature and Nurture
20.4K
Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
20.4K


