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Updated: Jun 13, 2025

Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level
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Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level

Published on: July 26, 2024

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在本质上是无序的原产地识别复杂区域内,通过简短的线性图案规范的复制许可

Yue Wu1, Qiongdan Zhang1, Yuhan Lin1

  • 1School of Biological Sciences, The University of Hong Kong, Hong Kong, China.

Nature communications
|September 13, 2024
PubMed
概括

酵母Orc2的N-终端内在无序区域对于DNA复制的启动至关重要. 这一区域的突变会损害复制前复合组合和ATP水解,阻碍细胞循环的进展.

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